Summary: The purpose of this review was to present the currently available information on oral appliance (OA) therapy for dentists, especially clinic-based dentists, to aid them in performing this treatment for the management of symptoms of obstructive sleep apnea (OSA).The clinical research evidence comprised of systematic reviews concerned with t
Magnetization transfer prepared gradient echo MRI for CEST imaging.
Chemical exchange saturation transfer (CEST) is an emerging MRI contrast mechanism that is capable of noninvasively Bergamot imaging dilute CEST agents and local properties such as pH and temperature, augmenting the routine MRI methods.However, the routine CEST MRI includes a long RF saturation pulse followed by fast image readout, which is associa
Two Separation-of-Function Isoforms of Human TPP1 Dictate Telomerase Regulation in Somatic and Germ Cells
Summary: Telomerase replicates chromosome ends in germ and somatic stem cells to facilitate their continued proliferation.Telomerase action depends on the telomeric protein TPP1, which recruits telomerase to telomeres and facilitates processive DNA synthesis.Here, we identify separation-of-function long (TPP1-L) and short (TPP1-S) isoforms of TPP1
Well Control Space Out: A Deep-Learning Approach for the Optimization of Drilling Safety Operations
As drilling of new oil and gas wells increase to meet energy demands, it is essential to Transport Chairs optimize processes to ensure the health and safety of the crew as well as the protection of the environment.Drilling operations represent a dynamic and challenging environment with natural and mechanical factors that need to be closely managed.